Synthesis of BIS(2.2,2-Trifluoroethyl) vinylphosphates /

Abstract

The focus of the research presented here is the synthesis, isolation and characterization of vinyl phosphates containing the bis(2,2,2-trifluoroethyl) group. The first step involved the synthesis of bis(2,2,2-trifluoroethoxy) phosphorochloridate. This reagent was then added to a ketone enolate, fonned by the reaction of LDA, prepared in situ from diisopropylamine and n-butyllithium, and a cyclic ketone to yield the desired vinyl phosphates.