dc.contributor.author |
Akula, Rakesh A. |
en_US |
dc.contributor.author |
Youngstown State University. College of Arts and Sciences. |
en_US |
dc.date.accessioned |
2011-01-31T14:20:04Z |
|
dc.date.accessioned |
2019-09-08T02:35:33Z |
|
dc.date.available |
2011-01-31T14:20:04Z |
|
dc.date.available |
2019-09-08T02:35:33Z |
|
dc.date.created |
2004 |
en_US |
dc.date.issued |
2004 |
en_US |
dc.identifier.other |
b19696000 |
en_US |
dc.identifier.uri |
http://jupiter.ysu.edu/record=b1969600 |
en_US |
dc.identifier.uri |
http://hdl.handle.net/1989/6308 |
|
dc.description |
x, 127 leaves : ill. ; 29 cm. |
en_US |
dc.description |
Thesis (M.S.)--Youngstown State University, 2004. |
en_US |
dc.description |
Includes bibliographical references (leaves 61-64). |
en_US |
dc.description.abstract |
The following work describes new pathways towards synthesis of sugar analogs that
may act as glycomimetics for the sugars present in bacteria that make capsular
polysaccharide. Two main approaches were investigated in the synthesis of N-glycosides.
Staudinger and aza-Wittig reactions provided an approach towards synthesis of glucosyl
imines. Another approach towards synthesis of N-glycosides involved Huisgen's 1,3-dipolar
cycloaddition of azides with alkynes in the presence of Cu(l) as catalyst. These reactions
were carried out in water as solvent to afford, regiospecifically, 1,4-disubsituted 1,2,3triazoles
in high yields. |
en_US |
dc.description.statementofresponsibility |
by Rakesh A. Akula. |
en_US |
dc.language.iso |
en_US |
en_US |
dc.relation.ispartofseries |
Master's Theses no. 0834 |
en_US |
dc.subject.classification |
Master's Theses no. 0834 |
en_US |
dc.subject.lcsh |
Glycosides--Synthesis. |
en_US |
dc.subject.lcsh |
Polysaccharides. |
en_US |
dc.subject.lcsh |
Azides. |
en_US |
dc.subject.lcsh |
Triazoles. |
en_US |
dc.title |
Approaches to pyranose carbohydrids / |
en_US |
dc.type |
Thesis |
en_US |