dc.contributor.author |
Del Signore, Heather. |
en_US |
dc.contributor.author |
Youngstown State University. Dept. of Chemistry. |
en_US |
dc.date.accessioned |
2011-01-31T14:20:06Z |
|
dc.date.accessioned |
2019-09-08T02:32:55Z |
|
dc.date.available |
2011-01-31T14:20:06Z |
|
dc.date.available |
2019-09-08T02:32:55Z |
|
dc.date.created |
2001 |
en_US |
dc.date.issued |
2001 |
en_US |
dc.identifier.other |
b19446731 |
en_US |
dc.identifier.uri |
http://jupiter.ysu.edu/record=b1944673 |
en_US |
dc.identifier.uri |
http://hdl.handle.net/1989/6310 |
|
dc.description |
xiii, 71 leaves : ill. ; 29 cm. |
en_US |
dc.description |
Thesis (M.S.)--Youngstown State University, 2001. |
en_US |
dc.description |
Includes bibliographical references (leaves 69-71). |
en_US |
dc.description.abstract |
Calixarenes are basket-shaped macromolecules comprised of phenolic
units arranged in a "cup" shaped conformation. Calixarenes have become the
interest in many areas of chromatography, specifically in reversed-phase HPLC.
The reason calixarenes are preferred is due to their ability to form host-guest
interactions with solute molecules during HPLC. When performing HPLC with a
calixarene stationary phase there is a different selectivity compared to a normal
C18 column.
An amino derived calix[4]arene was successfully attached to a sHica-gel
stationary phase. This new reversed phase material demonstrated the expected
host-guest interactions as evidenced by the non-linear relationship of the log k'
versus number of carbon atoms generated plots. To ensure that these were in
fact host-guest interactions and not only mixed-mode retention, which also is
shown by tailing peaks, comparison data of before and after endcapping was
presented. The endcapping step was necessary to cover the reactive free silanol
groups because of the known ability for the free silanol groups to cause mixedmode
retention. The data from the calix-derived silica was compared to a
commercial C18 bonded phase. This research shows that amines can easily be
linked to aminopropyl silica gels using glutaraldehyde as a linker. |
en_US |
dc.description.statementofresponsibility |
by Heather Del Signore. |
en_US |
dc.language.iso |
en_US |
en_US |
dc.relation.ispartofseries |
Master's Theses no. 0719 |
en_US |
dc.subject.classification |
Master's Theses no. 0719 |
en_US |
dc.subject.lcsh |
Calixarenes. |
en_US |
dc.subject.lcsh |
High performance liquid chromatography. |
en_US |
dc.title |
Synthesis and characterization of an HPLC stationary phase based on tert-butyl-tetra-[2-aminoethoxy]calix[4]arene / |
en_US |
dc.type |
Thesis |
en_US |