Reactive oxygen species (ROS) are compounds that are produced by the reduction of molecular oxygen; these species can generate free radicals. Metal-catalyzed oxidation systems are experimental systems that use a metal ion, ...
Systems utilizing transition metal ions such as iron and copper are responsible for the production of free radicals such as hydroxyl ions via the Fenton reaction. Free radicals and the resulting oxidative damage have been ...
Although oxidative damage to proteins by reactive oxygen species is significant in many diseases, there are many open questions regarding the site - specificity of this damage by reactive oxygen species. The highly reactive ...