Synthesis of diverse compounds using mannofuranose as a chiral scaffold /

Abstract

This project involves the convenient methods for the synthesis of mannofuranose derivatives. The parallel synthesis method provided an advantage to multiple compound synthesis of N-glycosides such as mannosyl triazoles. The synthesis of N-glycoside analogs from available precursors is studied using Hllisgen l,3-dipolar cyc1oadditions and the modified catalyst version. Manipulation of the isopropylidene protecting groups on mannose is also explored. The methods and results of each compound obtained are described in detail.